Tumor-suppressive microRNA-206 as a dual inhibitor of MET and EGFR oncogenic signaling in lung squamous cell carcinoma.

Abstract

Expression of the oncogene hepatocyte growth factor receptor (MET) and phosphorylation of the MET protein have been associated with both primary and acquired resistance to tyrosine kinase inhibitors (TKIs) used in therapy targeting the epidermal growth factor receptor (EGFR) in patients with non-small cell lung cancers (NSCLCs). Therefore, simultaneous… (More)
DOI: 10.3892/ijo.2014.2802

Topics

10 Figures and Tables

Cite this paper

@article{Mataki2015TumorsuppressiveMA, title={Tumor-suppressive microRNA-206 as a dual inhibitor of MET and EGFR oncogenic signaling in lung squamous cell carcinoma.}, author={Hiroko Mataki and Naohiko Seki and Takeshi Chiyomaru and Hideki Enokida and Yusuke Goto and Tomohiro Kumamoto and Kentaro Machida and Keiko Mizuno and Masayuki Nakagawa and Hiromasa Inoue}, journal={International journal of oncology}, year={2015}, volume={46 3}, pages={1039-50} }