Tumor-suppressive microRNA-143/145 cluster targets hexokinase-2 in renal cell carcinoma.

@article{Yoshino2013TumorsuppressiveMC,
  title={Tumor-suppressive microRNA-143/145 cluster targets hexokinase-2 in renal cell carcinoma.},
  author={Hirofumi Yoshino and Hideki Enokida and Toshihiko Itesako and Satoko Kojima and Takashi Kinoshita and Shuichi Tatarano and Takeshi Chiyomaru and Masayuki Nakagawa and Naohiko Seki},
  journal={Cancer science},
  year={2013},
  volume={104 12},
  pages={1567-74}
}
Our recent studies of microRNA (miRNA) expression signatures have indicated that the miR-143/145 cluster is significantly downregulated in several types of cancer and represents a putative tumor-suppressive miRNA in human cancers. The aim of this study was to investigate the functional significance of the miR-143/145 cluster in cancer cells and to identify… CONTINUE READING