Tumor suppressive miR-124 targets androgen receptor and inhibits proliferation of prostate cancer cells

@article{Shi2013TumorSM,
  title={Tumor suppressive miR-124 targets androgen receptor and inhibits proliferation of prostate cancer cells},
  author={X Shi and Liang A. Xue and A-H Ma and Clifford G Tepper and Regina F. Gandour-Edwards and H-J Kung and Ralph W. deVere White},
  journal={Oncogene},
  year={2013},
  volume={32},
  pages={4130-4138}
}
Although prostate cancer (CaP) is the most frequently diagnosed malignant tumor in American men, the mechanisms underlying the development and progression of CaP remain largely unknown. Recent studies have shown that downregulation of the microRNA miR-124 occurs in several types of human cancer, suggesting a tumor suppressive function of miR-124. Until now, however, it has been unclear whether miR-124 is associated with CaP. In the present study, we completed a series of experiments to… CONTINUE READING
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