Tumor suppressive functions of ceramide: evidence and mechanisms


Studies over the past two decades have identified ceramide as a multifunctional central molecule in the sphingolipid biosynthetic pathway. Given its diverse tumor suppressive activities, molecular understanding of ceramide action will produce fundamental insights into processes that limit tumorigenesis and may identify key molecular targets for therapeutic… (More)
DOI: 10.1007/s10495-015-1109-1


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