Tumor stage, human papillomavirus and smoking status affect the survival of patients with oropharyngeal cancer: an Italian validation study.

@article{Granata2012TumorSH,
  title={Tumor stage, human papillomavirus and smoking status affect the survival of patients with oropharyngeal cancer: an Italian validation study.},
  author={Roberta Granata and Rosalba Miceli and Ester Maria Orlandi and Francesco Perrone and Barbara Cortelazzi and Marzia Franceschini and Laura Deborah Locati and Paolo Bossi and Cristiana Bergamini and Aurora Mirabile and Luigi Mariani and Patrizia Olmi and Gabriele Scaramellini and Paolo Potepan and Pasquale Quattrone and K. Kian Ang and Lisa Licitra},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={2012},
  volume={23 7},
  pages={1832-7}
}
BACKGROUND Tumor human papillomavirus (HPV) status strongly affects overall survival (OS) of oropharyngeal cancer (OPC) patients. Recently, three groups with different outcomes were identified based on HPV status, smoking history and tumor stage. Our objective was to validate this model using a single-institutional retrospective database. PATIENTS AND METHODS Patients (n=120) diagnosed with OPC at our institution, treated with concomitant cisplatin plus radiotherapy (RT) (n=64), induction… CONTINUE READING
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