Tumor-specific protein human galectin-1 interacts with anticancer agents.


The present work shows a novel binding activity of the tumor specific lectin--recombinant human galectin-1 (hGal-1)--to three porphyrin compounds: (1) Zn-porphyrin (ZnTPPS); (2) Mn-porphyrin and (3) Au-porphyrin. These compounds are widely applied in the photodynamic therapy of cancer (PDT). Our data indicate that hGal-1, similar to some plant lectins, a… (More)
DOI: 10.1039/b905921k


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@article{dAuria2009TumorspecificPH, title={Tumor-specific protein human galectin-1 interacts with anticancer agents.}, author={Sabato d'Auria and Lidia Petrova and Constance M. John and George Russev and Antonio Varriale and Vanya Petkova Bogoeva}, journal={Molecular bioSystems}, year={2009}, volume={5 11}, pages={1331-6} }