Tumor-specific exon creation of the HELLS/SMARCA6 gene in non-small cell lung cancer.

@article{Yano2004TumorspecificEC,
  title={Tumor-specific exon creation of the HELLS/SMARCA6 gene in non-small cell lung cancer.},
  author={Masaaki Yano and Mamoru Ouchida and Hisayuki Shigematsu and Noriyoshi Tanaka and Koichi Ichimura and Kazuyasu Kobayashi and Yasuhiko Inaki and Shinichi Toyooka and Kazunori Tsukuda and Nobuyoshi Shimizu and Kenji Shimizu},
  journal={International journal of cancer},
  year={2004},
  volume={112 1},
  pages={8-13}
}
To identify tumor-suppressor genes on chromosome 10 in non-small cell lung cancers, we isolated 10 types of splicing variant of the HELLS/SMARCA6 gene transcripts. HELLS/SMARCA6 is a novel member of SNF2 family, which is implicated in cellular functions like chromatin remodeling. Variant 1 was an alternatively spliced isoform containing an insertion of a 44… CONTINUE READING