Tumor-specific but not nonspecific cell-free circulating DNA can be used to monitor disease response in lymphoma.

@article{Jones2012TumorspecificBN,
  title={Tumor-specific but not nonspecific cell-free circulating DNA can be used to monitor disease response in lymphoma.},
  author={Kimberley A Jones and Jamie P. Nourse and Colm Keane and Pauline Crooks and D. Gottlieb and D. Stuart Ritchie and Devinder S Gill and Maher K Gandhi},
  journal={American journal of hematology},
  year={2012},
  volume={87 3},
  pages={258-65}
}
Recently, nontumor specific circulating DNA was shown to be elevated in a broad range of lymphomas, implicating a role as a potential biomarker. Epstein-Barr virus' (EBV) presence within a proportion of lymphomas implies EBV-DNA has potential as a lymphoma-specific disease response biomarker. However, application would be restricted to EBV-associated lymphomas. Neither detailed comparison has been performed of lymphoma-specific versus nonspecific DNA as disease response biomarkers nor have the… CONTINUE READING
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