Tumor-related leukocytosis is associated with poor radiation response and clinical outcome in uterine cervical cancer patients.

@article{Cho2016TumorrelatedLI,
  title={Tumor-related leukocytosis is associated with poor radiation response and clinical outcome in uterine cervical cancer patients.},
  author={Young Joo Cho and Ki Hoon Kim and Hong In Yoon and Gwi Eon Kim and Yong Bae Kim},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={2016},
  volume={27 11},
  pages={2067-2074}
}
BACKGROUND To evaluate response to radiation and clinical outcome of uterine cervical cancer patients with tumor-related leukocytosis (TRL) at initial diagnosis and during definitive radiotherapy. PATIENTS AND METHODS We retrospectively analyzed 2456 patients with stage IA-IVA uterine cervical cancer who received definitive radiotherapy with (37.4%) or without (62.6%) platinum-based chemotherapy between 1986 and 2012. TRL was defined as two or more occurrences of leukocytosis over 9000/μl at… CONTINUE READING

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