Tumor perfusion-related parameter of diffusion-weighted magnetic resonance imaging: correlation with histological microvessel density.

@article{Lee2014TumorPP,
  title={Tumor perfusion-related parameter of diffusion-weighted magnetic resonance imaging: correlation with histological microvessel density.},
  author={Hye-Jeong Lee and Sun Young Rha and Yong Eun Chung and Hyo Sub Shim and Young Jin Kim and Jin Hur and Yoo Jin Hong and Byoung Wook Choi},
  journal={Magnetic resonance in medicine},
  year={2014},
  volume={71 4},
  pages={1554-8}
}
PURPOSE We obtained intravoxel incoherent motion (IVIM) parameters through biexponential analysis on diffusion-weighted MR imaging (DWI) using multiple b values. Correlation was evaluated between these parameters and histological microvessel density (MVD) for the possibility of noninvasive evaluation of MVD with DWI. METHODS Twenty-five nude mice with the HT29 colorectal cancer cells implanted were analyzed after undergoing DWI with multiple b values (0, 50, 100, 300, 500, 700, and 1000 s/mm… CONTINUE READING
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