Tumor oximetry: demonstration of an enhanced dynamic mapping procedure using fluorine-19 echo planar magnetic resonance imaging in the Dunning prostate R3327-AT1 rat tumor.

@article{Hunjan2001TumorOD,
  title={Tumor oximetry: demonstration of an enhanced dynamic mapping procedure using fluorine-19 echo planar magnetic resonance imaging in the Dunning prostate R3327-AT1 rat tumor.},
  author={Sandeep Hunjan and Dawen Zhao and Anca Constantinescu and Eric W. Hahn and Peter P. Antich and Ralph P. Mason},
  journal={International journal of radiation oncology, biology, physics},
  year={2001},
  volume={49 4},
  pages={1097-108}
}
PURPOSE We have developed an enhanced approach to measuring regional oxygen tension (pO(2)) dynamics in tumors. The technique is demonstrated in a group of 8 Dunning prostate rat tumors (R3327-AT1) with respect to respiratory challenge. METHODS AND MATERIALS Hexafluorobenzene was injected directly into the tumors of anesthetized rats. (19)F nuclear magnetic resonance echo planar imaging relaxometry was performed to obtain maps of regional tumor oxygenation under baseline conditions and when… CONTINUE READING
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