Tumor necrosis factor-related apoptosis-inducing ligand-mediated activation of mitochondria-associated nuclear factor-kappaB in prostatic carcinoma cell lines.

@article{Guseva2004TumorNF,
  title={Tumor necrosis factor-related apoptosis-inducing ligand-mediated activation of mitochondria-associated nuclear factor-kappaB in prostatic carcinoma cell lines.},
  author={Natalya V. Guseva and Agshin F. Taghiyev and Mary T Sturm and Oskar W. Rokhlin and Michael B. Cohen},
  journal={Molecular cancer research : MCR},
  year={2004},
  volume={2 10},
  pages={574-84}
}
It has been suggested that some nuclear transcription factors may participate in the regulation of mitochondrial functions through transcriptional control of mitochondrial DNA. Very little is known about the response of transcription factors within mitochondria to the activation of death receptors. Recent publications indicate that nuclear factor-kappaB (NF-kappaB) is localized in mitochondria of mammalian cells. Because of the critical role of mitochondria in the execution of many apoptotic… CONTINUE READING
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