Tumor necrosis factor receptor cross-talk.

  title={Tumor necrosis factor receptor cross-talk.},
  author={Petrus J W Naud{\'e} and Johan A. den Boer and Paul G. M. Luiten and Ulrich L. M. Eisel},
  journal={The FEBS journal},
  volume={278 6},
Extensive research has been performed to unravel the mechanistic signaling pathways mediated by tumor necrosis factor receptor 1 (TNFR1), by contrast there is limited knowledge on cellular signaling upon activation of TNFR2. Recently published data have revealed that these two receptors not only function independently, but also can influence each other via cross-talk between the different signaling pathways initiated by TNFR1 and TNFR2 stimulation. Furthermore, the complexity of this cross-talk… CONTINUE READING