Tumor necrosis factor and severe malaria.

  title={Tumor necrosis factor and severe malaria.},
  author={Nathan Shaffer and Georges Emile Raymond Grau and Kristina Hedberg and Farzin Davachi and B Lyamba and Allen W. Hightower and Joel G. Breman and N D Phuc},
  journal={The Journal of infectious diseases},
  volume={163 1},
To investigate the relation of tumor necrosis factor-alpha (TNF alpha) to Plasmodium falciparum infection, plasma TNF alpha concentrations were measured in Zairian children with severe malaria, mild malaria, or other illnesses. The initial geometric mean plasma concentration of TNF alpha among 61 children with P. falciparum infection, (71 pg/ml) was higher than the level in 26 severely ill, aparasitemic children (10 pg/ml; P less than .001). Among 29 parasitemic children, initial geometric mean… CONTINUE READING

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