Tumor necrosis factor-alpha antagonists twenty years later: what do Cochrane reviews tell us?


In 1998, the U.S. Food and Drug Administration granted regulatory approval to the first tumor necrosis factor-α antagonist, infliximab, for the treatment of moderately to severely active Crohn's disease. As of 2013, there were 3 additional tumor necrosis factor-α antagonists commercially available for the treatment of inflammatory bowel disease in the… (More)
DOI: 10.1097/MIB.0000000000000218


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