Tumor microsatellite instability and clinicopathologic features in Iranian colorectal cancer patients at risk for Lynch syndrome

@inproceedings{Zeinalian2015TumorMI,
  title={Tumor microsatellite instability and clinicopathologic features in Iranian colorectal cancer patients at risk for Lynch syndrome},
  author={Mehrdad Zeinalian and Morteza Hashemzadeh-Chaleshtori and Rasoul Salehi and Mohammad Taghi Kazemi and Mohammad Hassan Emami},
  booktitle={Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences},
  year={2015}
}
BACKGROUND Microsatellite instability (MSI) is a mutational signature that is the hallmark of Lynch syndrome, and MSI testing is a cost-effective method to screen the disease. Since there is no enough data about MSI status and associated clinicopathologic features of hereditary nonpolyposis colorectal cancer (HNPCC) in Iran, our study is a new trial to describe them in center of Iran (Isfahan). MATERIALS AND METHODS It is a descriptive retrospective study to screen HNPCC families using… CONTINUE READING