Tumor localizing agents. V. Radioiodinated pregnanes.

@article{Counsell1968TumorLA,
  title={Tumor localizing agents. V. Radioiodinated pregnanes.},
  author={R. Counsell and B. H. Hong and R. Willette and V. Ranade},
  journal={Steroids},
  year={1968},
  volume={11 6},
  pages={
          817-26
        }
}
Previous studies with progesterone-4-14C suggested that a radioiodinated analog might be useful for photoscanning the adrenal gland and associated tumors. 21-Iodoprogesterone was prepared by conversion of deoxycorticosterone to its mesylate and subsequent displacement with iodide. Depending on the conditions for mesylation, 21-chloroprogesterone could also be isolated. 21-Iodopregnenolone acetate was obtained in a similar manner from the 21-bromo analog which in turn was prepared in good yield… Expand
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