Tumor initiating potential of side population cells in human gastric cancer.

@article{Fukuda2009TumorIP,
  title={Tumor initiating potential of side population cells in human gastric cancer.},
  author={Kazumasa Fukuda and Yoshiro Saikawa and Masaki Ohashi and Koshi Kumagai and Masaki Kitajima and Hideyuki Okano and Yumi Matsuzaki and Yuko Kitagawa},
  journal={International journal of oncology},
  year={2009},
  volume={34 5},
  pages={1201-7}
}
Side population (SP) cells are a small subpopulation of cells with enriched source of gastric tumor-initiating cells (TICs) with stem-like cell property that are characterized by high efflux ability of Hoechst 33342 dye, reflecting high expression of several subtypes of the ATP-binding cassette transporter family that is characteristic of stem cells. The present study is the first to discover and characterize SP cells within gastric cancer (GC) tumors. In this study, human GC cell lines (MKN45… CONTINUE READING