Tumor-infiltrating γδ T lymphocytes predict clinical outcome in human breast cancer.

@article{Ma2012TumorinfiltratingT,
  title={Tumor-infiltrating γδ T lymphocytes predict clinical outcome in human breast cancer.},
  author={Chunling Ma and Qunyuan Zhang and Jian Ye and Fenghua Wang and Yanping Zhang and Eric Wevers and Theresa Schwartz and Pamela Hunborg and Mark A Varvares and Daniel F. Hoft and Eddy C Hsueh and Guangyong Peng},
  journal={Journal of immunology},
  year={2012},
  volume={189 10},
  pages={
          5029-36
        }
}
Understanding and dissecting the role of different subsets of regulatory tumor-infiltrating lymphocytes (TILs) in the immunopathogenesis of individual cancer is a challenge for anti-tumor immunotherapy. High levels of γδ regulatory T cells have been discovered in breast TILs. However, the clinical relevance of these intratumoral γδ T cells is unknown. In this study, γδ T cell populations were analyzed by performing immunohistochemical staining in primary breast cancer tissues from patients with… CONTINUE READING
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