Tumor imaging using a standardized radiolabeled adapter protein docked to vascular endothelial growth factor.

Abstract

UNLABELLED Direct radiolabeling of proteins can result in the loss of targeting activity, requires highly customized procedures, and yields heterogeneous products. Here we describe a novel imaging complex comprised of a standardized (99m)Tc-radiolabeled adapter protein noncovalently bound to a "Docking tag" fused to a "Targeting protein". The assembly of… (More)

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Cite this paper

@article{Blankenberg2004TumorIU, title={Tumor imaging using a standardized radiolabeled adapter protein docked to vascular endothelial growth factor.}, author={Francis Blankenberg and Stefanie J. Mandl and Yu-an Cao and Caitlin E O'Connell-Rodwell and Christopher H. Contag and Carina Mar{\'i} and Timur I. Gaynutdinov and J L Vanderheyden and Marina V. Backer and Joseph M Backer}, journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine}, year={2004}, volume={45 8}, pages={1373-80} }