Tumor growth dynamics: insights into evolutionary processes.

@article{RodriguezBrenes2013TumorGD,
  title={Tumor growth dynamics: insights into evolutionary processes.},
  author={Ignacio A. Rodriguez-Brenes and Natalia L. Komarova and Dominik Wodarz},
  journal={Trends in ecology & evolution},
  year={2013},
  volume={28 10},
  pages={
          597-604
        }
}
Identifying the types of event that drive tumor evolution and progression is crucial for understanding cancer. We suggest that the analysis of tumor growth dynamics can provide a window into tumor biology and evolution by connecting them with the types of genetic change that have occurred. Although fundamentally important, the documentation of tumor growth kinetics is more sparse in the literature than is the molecular analysis of cells. Here, we provide a historical summary of tumor growth… CONTINUE READING
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