Tumor escape from immune response: mechanisms and targets of activity.

  title={Tumor escape from immune response: mechanisms and targets of activity.},
  author={Dmitry I Gabrilovich and Vladimir Pisarev},
  journal={Current drug targets},
  volume={4 7},
Immune system plays an important role in control of tumor progression. Effective antitumor immune response depends on close interaction of several elements of immune system. They include antigen-presenting cells, different subsets of T cells, B cells and NK cells. However, tumor cells developed a number of mechanisms to escape recognition and elimination by immune system. In this review we will discuss these mechanisms and address possible approaches to correct them. 
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