Tumor eradication by hepatitis B virus X antigen-specific CD8+ T cells in xenografted nude mice.

Abstract

We have previously reported several CTL epitopes derived from the hepatitis B viral X Ag (HBx). In this study, we evaluated whether HBx-specific CTLs can be effectively used in adoptive cancer immunotherapy. To validate the possibility, four peptides containing a HLA-A2.1-restricted binding consensus motif were identified from the HBx protein and tested for… (More)

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@article{Chun2003TumorEB, title={Tumor eradication by hepatitis B virus X antigen-specific CD8+ T cells in xenografted nude mice.}, author={Eunyoung Chun and Jihyun Lee and Hong Seok Cheong and Ki-Young Lee}, journal={Journal of immunology}, year={2003}, volume={170 3}, pages={1183-90} }