Tumor cell type can be reproducibly diagnosed and is of independent prognostic significance in patients with maximally debulked ovarian carcinoma.

@article{Gilks2008TumorCT,
  title={Tumor cell type can be reproducibly diagnosed and is of independent prognostic significance in patients with maximally debulked ovarian carcinoma.},
  author={C. Blake Gilks and Diana N. Ionescu and Steve E Kalloger and Martin K{\"o}bel and Julie Irving and Blaise Clarke and Jennifer Santos and Nhu Tuyen Le and Veronika Moravan and Kenneth D. Swenerton},
  journal={Human pathology},
  year={2008},
  volume={39 8},
  pages={1239-51}
}
Ovarian surface epithelial carcinomas are routinely subclassified by pathologists based on tumor cell type and grade. It is controversial whether cell type or grade is superior in predicting patient response to treatment or survival, in patients stratified by stage of disease. The aim of this study was to uniformly apply updated criteria for cell-type and grade assignment to a series of 575 cases of ovarian surface epithelial carcinoma. All patients were optimally surgically debulked, with no… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 102 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 44 references

World Health Organization classification of tumours: Pathology and genetics. Tumours of the breast and female genital organs

  • FA Tavassoli, P Devilee, editors
  • 2003
Highly Influential
4 Excerpts

Mutational analysis of K-ras segregates ovarian serous carcinomas into two types: invasive MPSC (low-grade tumor) and conventional serous carcinoma (high-grade tumor)

  • G Singer, M Shih Ie, A Truskinovsky, H Umudum, RJ. Kurman
  • Int J Gynecol Pathol 2003;22:37-41
  • 2003
Highly Influential
5 Excerpts

Inter-observer and intraobserver variability of a two-tier system for grading ovarian serous carcinoma

  • A Malpica, MT Deavers, C Tomos
  • Am J Surg Pathol
  • 2007
1 Excerpt

Similar Papers

Loading similar papers…