Tumor-cell-induced platelet aggregation is a glycoprotein-dependent and lipoxygenase-associated process.

@article{Bastida1987TumorcellinducedPA,
  title={Tumor-cell-induced platelet aggregation is a glycoprotein-dependent and lipoxygenase-associated process.},
  author={Eva Bastida and Lourdes Almirall and Antonio Pern{\'i}a Ordinas},
  journal={International journal of cancer},
  year={1987},
  volume={39 6},
  pages={
          760-3
        }
}
To characterize the platelet receptor sites and the platelet metabolic pathways involved in tumor-cell-induced platelet aggregation, we have used a homologous system consisting of human platelets and 2 tumor cell lines of human origin, which activate platelets through different mechanisms. Preincubation of platelets with an MAb against platelet glycoprotein Ib partially blocked tumor-cell-induced platelet aggregation, and preincubation of platelets with an MAb against the glycoprotein complex… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 19 CITATIONS

Platelets and their role in cancer evolution and immune system.

  • Translational lung cancer research
  • 2015
VIEW 3 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Role of platelets and platelet receptors in cancer metastasis

  • Journal of Hematology & Oncology
  • 2018
VIEW 2 EXCERPTS
CITES BACKGROUND

Patterns and functional implications of platelets upon tumor "education".

  • The international journal of biochemistry & cell biology
  • 2017
VIEW 1 EXCERPT
CITES BACKGROUND

Similar Papers

Loading similar papers…