Tumor cell binding and induction of endothelial cell tumoricidal activity in vitro by muramyl dipeptide is enhanced by liposomal encapsulation.

@article{Phillips1994TumorCB,
  title={Tumor cell binding and induction of endothelial cell tumoricidal activity in vitro by muramyl dipeptide is enhanced by liposomal encapsulation.},
  author={N. C. Phillips and J L Stewart-Phillips and Pu Wang},
  journal={Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy},
  year={1994},
  volume={15 3},
  pages={185-93}
}
We investigated the ability of phosphatidylcholine (PC):phosphatidylserine (PS) liposomes containing muramyl dipeptide (MDP) to enhance tumor cell binding and induction of vascular endothelial cell tumoricidal activity in vitro against syngeneic B16-BL6 melanoma tumor cells. Endothelial cell-liposome interaction was influenced by the proportion of PS in the… CONTINUE READING