Tumor cell arrest in the microcirculation: lack of evidence for a leukocyte-like rolling adhesive interaction with vascular endothelium in vivo.

@article{Thorlacius1997TumorCA,
  title={Tumor cell arrest in the microcirculation: lack of evidence for a leukocyte-like rolling adhesive interaction with vascular endothelium in vivo.},
  author={Henrik Thorlacius and Jes{\'u}s Prieto and Johan Raud and Narinder Kumar Gautam and Manuel Elkin Patarroyo and Per Hedqvist and Lennart Lindbom},
  journal={Clinical immunology and immunopathology},
  year={1997},
  volume={83 1},
  pages={68-76}
}
Hematogenous spread of tumor cells and metastasis formation in secondary organs are insidious aspects of cancer. In the present intravital microscopic study in the rabbit mesentery, we examined the in vivo flow behavior of six human tumor cell lines of different histological origin. The tumor cells and human neutrophils were injected locally into a side branch of the superior mesenteric artery upstream of the observed microvascular area in the mesentery. None of the tumor cells behaved similar… CONTINUE READING

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