Tumor cell adhesive mechanisms and their relationship to metastasis.

Abstract

Despite recent advances in the diagnosis and therapy of many forms of cancer, metastasis remains the major cause of death in cancer patients. As tumors progress they become increasingly heterogeneous, giving rise to aggressive subpopulations of tumor cells that subsequently invade local tissues, the lymphatics, and the circulatory system. This invasive… (More)

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Cite this paper

@article{McCarthy1991TumorCA, title={Tumor cell adhesive mechanisms and their relationship to metastasis.}, author={J. B. McCarthy and Amy P N Skubitz and J. Iida and David Mooradian and Markus Wilke and Leo T. Furcht}, journal={Seminars in cancer biology}, year={1991}, volume={2 3}, pages={155-67} }