Tumor budding in colorectal cancer revisited: results of a multicenter interobserver study

  title={Tumor budding in colorectal cancer revisited: results of a multicenter interobserver study},
  author={Viktor H Koelzer and Inti Zlobec and Martin David Berger and Gieri Cathomas and Heather E. Dawson and Klaus Dirschmid and Marion Haedrich and Daniel Inderbitzin and Felix Albert Offner and Giacomo Dr Puppa and Walter Seelentag and Beat Schn{\"u}riger and Luigi Tornillo and Alessandro Lugli},
  journal={Virchows Archiv},
Tumor budding in colorectal cancer (CRC) is recognized as a valuable prognostic factor but its translation into daily histopathology practice has been delayed by lack of agreement on the optimal method of assessment. Within the context of the Swiss Association of Gastrointestinal Pathology (SAGIP), we performed a multicenter interobserver study on tumor budding, comparing hematoxylin and eosin (H&E) with pan-cytokeratin staining using a 10 high power field (10HPF) and hotspot (1HPF) method. Two… CONTINUE READING
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Pathology and prognostic determinants of colorectal cancer

  • C Compton
  • 2014
1 Excerpt

Tumor budding in the clinical management of colon and rectal cancer

  • VH Koelzer, I Zlobec, A Lugli
  • Colorectal Cancer
  • 2014
1 Excerpt

Proposal for a 10-high-power-fields scoring method for the assessment of tumor budding in colorectal cancer

  • E Karamitopoulou, I Zlobec, +4 authors A Lugli
  • Modern Pathol: Off J U S Can Acad Pathol,
  • 2013
1 Excerpt

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