Tumor-associated macrophages provide a suitable microenvironment for non-small lung cancer invasion and progression.

@article{Wang2011TumorassociatedMP,
  title={Tumor-associated macrophages provide a suitable microenvironment for non-small lung cancer invasion and progression.},
  author={Rui Wang and Jie Zhang and Sufeng Chen and Meng S Lu and Xiaoyang Luo and Shihua Yao and Shilei Liu and Ying Qin and Haiquan Chen},
  journal={Lung cancer},
  year={2011},
  volume={74 2},
  pages={188-96}
}
OBJECTIVE It remains largely unknown whether tumor-associated macrophages (TAMs) are involved in invasion and metastasis of human lung cancer. The aim of our study was to obtain an accurate overview of the broad range of changes occurring in monocytes that develop into TAMs, and the roles of TAMs during the progression of non-small cell lung cancer. METHODS TAM was isolated from 98 primary lung cancer tissues by short term cultivation in serum-free medium. The mRNA expression levels of 9… CONTINUE READING
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