Tumor associated macrophages in relapsed and refractory Hodgkin lymphoma.

@article{Casulo2013TumorAM,
  title={Tumor associated macrophages in relapsed and refractory Hodgkin lymphoma.},
  author={Carla Casulo and Maria E. Arcila and Olga L. Bohn and Julie Teruya-Feldstein and Jocelyn C Maragulia and Craig H. Moskowitz},
  journal={Leukemia research},
  year={2013},
  volume={37 9},
  pages={1178-83}
}
BACKGROUND Growing evidence demonstrates that an increased number of CD68 positive tumor-associated macrophages (TAM) is associated with decreased survival in patients with newly diagnosed classic Hodgkin lymphoma (HL). However, the impact of TAM in relapsed and refractory disease is unknown. DESIGN AND METHODS To investigate whether the presence of elevated CD68 retains its prognostic significance in the relapsed and refractory setting, we analyzed pre-salvage biopsy specimens of 81 patients… CONTINUE READING
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