Tumor angiogenesis in advanced stage ovarian carcinoma.

  title={Tumor angiogenesis in advanced stage ovarian carcinoma.},
  author={H C Hollingsworth and Elise C. Kohn and Seth Steinberg and Mace L. Rothenberg and Mar{\'i}a Jos{\'e} Beato Merino},
  journal={The American journal of pathology},
  volume={147 1},
Tumor angiogenesis has been found to have prognostic significance in many tumor types for predicting an increased risk of metastasis. We assessed tumor vascularity in 43 cases of advanced stage (International Federation of Gynecologists and Obstetricians stages III and IV) ovarian cancer by using the highly specific endothelial cell marker CD34. Microvessel counts and stage were associated with disease-free survival and with overall survival by Kaplan-Meier analysis. The plots show that higher… CONTINUE READING

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