Tumor angiogenesis as a prognostic factor in early oral tongue cancer.

  title={Tumor angiogenesis as a prognostic factor in early oral tongue cancer.},
  author={Thomas Shpitzer and Moshe Chaimoff and Rivka Gal and Yoram Stern and Rafael Feinmesser and K. N. Segal},
  journal={Archives of otolaryngology--head & neck surgery},
  volume={122 8},
OBJECTIVE To evaluate the relationship between tumor angiogenesis and the subsequent development of cervical node metastases in patients with stage 1 carcinoma of the oral tongue. METHODS The study group consisted of 25 patients with T1 carcinoma with no evidence of neck disease at presentation. Paraffin blocks from 10 patients, in whom neck node metastases were found shortly after surgery, were stained for factor VIII and compared with those from 10 randomly chosen patients in whom no… CONTINUE READING


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