Tumor angiogenesis as a predictor of recurrence and survival in patients with node-negative colon cancer.

@article{Frank1995TumorAA,
  title={Tumor angiogenesis as a predictor of recurrence and survival in patients with node-negative colon cancer.},
  author={R E Frank and Theodore John Saclarides and S E Leurgans and N J Speziale and Edyta Drab and David B Rubin},
  journal={Annals of surgery},
  year={1995},
  volume={222 6},
  pages={695-9}
}
OBJECTIVE The authors' objective was to quantitatively assess angiogenesis or neovascularity within node-negative colon cancers and to determine if increased angiogenesis correlated with higher recurrence and lower survival rates. SUMMARY BACKGROUND DATA Neovascularization promotes rapid tumor growth by facilitating nutrient and metabolite exchange. Recent work with breast and nonsmall cell lung cancers has shown that low angiogenic activity imparts a lower risk of recurrence and metastasis… CONTINUE READING
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