Tumor angiogenesis activity in cells grown in tissue culture.

@article{Klagsbrun1976TumorAA,
  title={Tumor angiogenesis activity in cells grown in tissue culture.},
  author={Michael Klagsbrun and David R. Knighton and J Folkman},
  journal={Cancer research},
  year={1976},
  volume={36 1},
  pages={110-4}
}
Normal, viral transformed and tumor-derived cells grown in tissue culture and representing different species were tested for their ability to produce an extracellular tumor angiogenesis factor (TAF). TAF was assayed by measuring the host-mediated vascular response of the chorioallantoic membrane to TAF preparations. All of the viral transformed and tumor-derived cells tested, including SVT2, SVW126, Welker 256 rat carcinoma, B-16 mouse melanoma, human glioblastoma, and human meningioma cells… CONTINUE READING

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