Tumor and serum gamma-glutamyl transpeptidase, new prognostic and molecular interpretation of an old biomarker in gastric cancer

@article{Wang2017TumorAS,
  title={Tumor and serum gamma-glutamyl transpeptidase, new prognostic and molecular interpretation of an old biomarker in gastric cancer},
  author={Qinchuan Wang and X. Shu and Yong Dong and Jichun Zhou and Rong-yue Teng and Jian-guo Shen and Yongxia Chen and M. Dong and Wenjun Zhang and Yasheng Huang and S. Xie and Qun Wei and Wenhe Zhao and Wen-jun Chen and Xiao-ming Yuan and Xuanchang Qi and Linbo Wang},
  journal={Oncotarget},
  year={2017},
  volume={8},
  pages={36171 - 36184}
}
Background Gastric Cancer is one of the most lethal malignancies worldwide. Gamma-glutamyl transpeptidase (GGT) is an enzyme mainly involved in cellular glutathione homeostasis. We aim to explore the clinical value of GGT in gastric cancer. Results Among 322 patients enrolled, 65/82 patients were determined as GGT positive in serum/tumor, respectively. High tumor GGT expression is significantly associated with lymph node metastasis, histological subtype, and Her2 expression. Kaplan-Meier curve… Expand
Serum gamma-glutamyltransferase and the overall survival of metastatic pancreatic cancer
...
1
2
...

References

SHOWING 1-10 OF 59 REFERENCES
Altered expression of gamma-glutamyl transpeptidase in human tumors.
γ‐Glutamyltransferase and cancer risk: The Korean cancer prevention study
Gamma glutamyltransferase and long-term survival: is it just the liver?
Diagnostic value of serum gamma-glutamyl transferase isoenzyme for hepatocellular carcinoma: a 10-year study.
Lin28 promotes Her2 expression and Lin28/Her2 predicts poorer survival in gastric cancer
A protein and mRNA expression-based classification of gastric cancer
Gamma-glutamyl transpeptidase immunoreactivity in benign and malignant breast tissue
...
1
2
3
4
5
...