Tumor Suppressors in Zebrafish: From TP53 to PTEN and Beyond.

@article{Hertog2016TumorSI,
  title={Tumor Suppressors in Zebrafish: From TP53 to PTEN and Beyond.},
  author={Jeroen den Hertog},
  journal={Advances in experimental medicine and biology},
  year={2016},
  volume={916},
  pages={87-101}
}
Zebrafish are increasingly being used to study cancer. Almost all tumor types have been found in zebrafish. However, tumor incidence is relatively low and tumors develop late in life. Functional inactivation of tumor suppressors is a crucial step in cancer progression and more and more tumor suppressor genes are being studied in zebrafish. Most often tumor… CONTINUE READING