Tumor Suppressor Genes (P16 and RASSF1A) Hypermethylation in Hepatocellular Carcinoma and Chronic Hepatitis C Patients

  • MOHAMMAD M. ATTA, MOHAMMAD E. EL-SHEWI, ENAS A. AHMAD
  • Published 2016

Abstract

Background: Hepatocellular carcinoma (HCC) is one of the most common cancer with high mortality rate requiring early diagnosis and treatment. Hepatocarcinogenesis is considered a multistep process in which DNA methylation is a type of epigenetic modification and the relationship between methylation and cancer have been the focus of molecular biology… (More)

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