Tumor-Related Exosomes Contribute to Tumor-Promoting Microenvironment: An Immunological Perspective

@inproceedings{Chen2017TumorRelatedEC,
  title={Tumor-Related Exosomes Contribute to Tumor-Promoting Microenvironment: An Immunological Perspective},
  author={Wuzhen Chen and Jingxin Jiang and Wenjie Xia and Jian Huang},
  booktitle={Journal of immunology research},
  year={2017}
}
Exosomes are a kind of cell-released membrane-form structures which contain proteins, lipids, and nucleic acids. These vesicular organelles play a key role in intercellular communication. Numerous experiments demonstrated that tumor-related exosomes (TEXs) can induce immune surveillance in the microenvironment in vivo and in vitro. They can interfere with the maturation of DC cells, impair NK cell activation, induce myeloid-derived suppressor cells, and educate macrophages into protumor… CONTINUE READING
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