Tumor Necrosis Factor and Alzheimer ’ s Disease : A Cause and Consequence Relationship

@inproceedings{Sharma2012TumorNF,
  title={Tumor Necrosis Factor and Alzheimer ’ s Disease : A Cause and Consequence Relationship},
  author={Vivek R. Sharma and Vinay Thakur and Shesh Nath Singh and Rajender Guleria},
  year={2012}
}
Tumor necrosis factor alpha (TNF) was discovered more than a century ago as endotoxin-induced glycoprotein, which causes haemorrhagic necrosis of sarcomas. Originally described as a circulating factor that causes necrosis of tumours,it now appears that TNF has diverse and critical roles to play in the pathogenic progression of a number of chronic inflammatory disorders, including rheumatoid arthritis, Crohn’s disease, psoriasis, Alzheimer’s disease, ischemic stroke, Parkinson’s disease… CONTINUE READING
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