Tumor Necrosis Factor-α in Human Milk

  title={Tumor Necrosis Factor-α in Human Milk},
  author={H Elizabeth Rudloff and Frank C. Schmalstieg and Akram A Mushtaha and Kimberly H. Palkowetz and Stephen K Liu and Armond S. Goldman},
  journal={Pediatric Research},
ABSTRACT: We previously demonstrated that certain biologic activities in human milk were partially blocked by antibodies directed against human tumor necrosis factor-α (TNF-α). In this study, immunochemical methods were used to verify the presence of TNF-α in human milk obtained during the first few days of lactation. Gel filtration revealed the presence of TNF-α by RIA in molecular weight fractions between 80 and 195 kD. TNF-α could not be detected consistently by conventional Western blotting… CONTINUE READING


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