Tumor Microenvironment and Myeloid-Derived Suppressor Cells

@article{Umansky2012TumorMA,
  title={Tumor Microenvironment and Myeloid-Derived Suppressor Cells},
  author={Viktor Umansky and Alexandra Sevko},
  journal={Cancer Microenvironment},
  year={2012},
  volume={6},
  pages={169-177}
}
Tumor progression has been demonstrated to be supported by chronic inflammatory conditions developed in the tumor microenvironment and characterized by the long-term secretion of various inflammatory soluble factors (including cytokines, chemokines, growth factors, reactive oxygen and nitrogen species, prostaglandins etc.) and strong leukocyte infiltration. Among leukocytes infiltrating tumors, myeloid-derived suppressor cells (MDSCs) represent one of the most important players mediating… CONTINUE READING

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