Tumor-Infiltrating Regulatory T Cells: Phenotype, Role, Mechanism of Expansion In Situ and Clinical Significance

Abstract

In immunocompetent individuals, the immune system initially eradicates potentially tumorigenic cells as they develop, a capacity that is progressively lost when malignant cells acquire alterations that sustain immunosubversion and/or immunoevasion. One of the major mechanisms whereby cancer cells block antitumor immune responses involves a specific class of… (More)
DOI: 10.1007/s12307-012-0122-y

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Cite this paper

@article{Tanchot2012TumorInfiltratingRT, title={Tumor-Infiltrating Regulatory T Cells: Phenotype, Role, Mechanism of Expansion In Situ and Clinical Significance}, author={Corine Tanchot and Magali Terme and H{\'e}l{\'e}ne P{\'e}r{\'e} and T. Tran and Nadine Benhamouda and Marius M. Strioga and Claire Banissi and Lrenzo Galluzzi and Guido Kroemer and Eric Tartour}, journal={Cancer Microenvironment}, year={2012}, volume={6}, pages={147-157} }