Tumor Hypoxia and Systemic Levels of Vascular Endothelial Growth Factor (VEGF) in Head and Neck Cancers

Abstract

Hypoxia is the most important stimulus for the up-regulation of vascular endothelial growth factor (VEGF), one of the key cytokines for angiogenesis. We have investigated the possible relationship between tumor hypoxia and systemic levels of VEGF. Patients and Methods: 56 patients with head and neck cancers underwent measurement of tumor volume… (More)
DOI: 10.1007/PL00002428

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