Tumor Delivery of Chemotherapy Combined with Inhibitors of Angiogenesis and Vascular Targeting Agents

@article{Cesca2013TumorDO,
  title={Tumor Delivery of Chemotherapy Combined with Inhibitors of Angiogenesis and Vascular Targeting Agents},
  author={Marta Cesca and Francesca Bizzaro and Massimo Zucchetti and Raffaella Giavazzi},
  journal={Frontiers in Oncology},
  year={2013},
  volume={3}
}
  • Marta Cesca, Francesca Bizzaro, +1 author Raffaella Giavazzi
  • Published 2013
  • Medicine
  • Frontiers in Oncology
  • Numerous angiogenesis-vascular targeting agents have been admitted to the ranks of cancer therapeutics; most are used in polytherapy regimens. This review looks at recent progress and our own preclinical experience in combining angiogenesis inhibitors, mainly acting on VEGF/VEGFR pathways, and vascular targeting agents with conventional chemotherapy, discussing the factors that determine the outcome of these treatments. Molecular and morphological modifications of the tumor microenvironment… CONTINUE READING

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