Tumor-Associated Macrophages in Glioma: Friend or Foe?

  title={Tumor-Associated Macrophages in Glioma: Friend or Foe?},
  author={Benjamin C Kennedy and Christopher R. Showers and David E. Anderson and Lisa M. Anderson and Peter Canoll and Jeffrey N. Bruce and Richard C. E. Anderson},
  booktitle={Journal of oncology},
Tumor-associated macrophages (TAMs) contribute substantially to the tumor mass of gliomas and have been shown to play a major role in the creation of a tumor microenvironment that promotes tumor progression. Shortcomings of attempts at antiglioma immunotherapy may result from a failure to adequately address these effects. Emerging evidence supports an independent categorization of glioma TAMs as alternatively activated M2-type macrophages, in contrast to classically activated proinflammatory M1โ€ฆย CONTINUE READING
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  • B. D. Choi, K. S. Chen, J. H. Sampson
  • Tumors of the Central Nervous System, M. A. Hayatโ€ฆ
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