Tubuloglomerular feedback in rat kidneys of different renin contents

  title={Tubuloglomerular feedback in rat kidneys of different renin contents},
  author={Roland M{\"u}ller-Suur and H. -U. Gutsche and K. F. Samwer and Wolfgang Oelkers and Klaus Hierholzer},
  journal={Pfl{\"u}gers Archiv},
Variations in flow rate through the loop of Henle in the range of 0–50 nl/min were induced using pressure controlled microperfusion. Simultaneously, with the aid of a second pressure-microperfusionsystem, the glomerular function of the same nephron was studied by continuous measurement of two parameters, early proximal flow rate (EPFR) and/or stop flow pressure (SFP). Elevation of loop perfusion above physiological values (40 nl/min) resulted in a drop of EPFR and SFP, whereas lowering… CONTINUE READING
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