Tubuloglomerular feedback and tubular reabsorption during acute potassium loading in rats.

  title={Tubuloglomerular feedback and tubular reabsorption during acute potassium loading in rats.},
  author={Branko Braam and Peter Boer and Hein A. Koomans},
  journal={The American journal of physiology},
  volume={267 2 Pt 2},
Acute hyperkalemia has been associated with changes in reabsorption, glomerular filtration rate (GFR), and autoregulation, which might represent altered tubuloglomerular feedback (TGF) responsiveness. Therefore, TGF responsiveness, segmental reabsorption of water, sodium and potassium, and single-nephron GFR were evaluated during acute potassium loading in male Sprague-Dawley rats. Rats receiving 300 mM KNO3, KHCO3, and KCl showed significantly increased plasma potassium levels and attenuation… 
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