Tubular nanofiber scaffolds for tissue engineered small-diameter vascular grafts.

@article{He2009TubularNS,
  title={Tubular nanofiber scaffolds for tissue engineered small-diameter vascular grafts.},
  author={Wei He and Zuwei Ma and Wee Eong Teo and Yi Xiang Dong and Peter Ashley Robless and Thiam Chye Lim and Seeram Ramakrishna},
  journal={Journal of biomedical materials research. Part A},
  year={2009},
  volume={90 1},
  pages={205-16}
}
Quick establishment of a confluent and stable endothelial cells (ECs) layer in the lumen of vascular grafts is critical for long-term patency of small-diameter vascular grafts. The objective of the study was to fabricate tubular nanofiber scaffolds, incorporate ECs onto the lumen of the scaffolds, and establish an animal model to prove the basic concept of using the scaffolds as vascular grafts. Poly(L-lactic acid)-co-poly(epsilon-caprolactone) P(LLA-CL 70:30) tubular nanofiber scaffolds were… CONTINUE READING