Tuberculous effusion: ADA activity correlates with CD4+ cell numbers in the fluid and the pleura.

@article{Gaga2005TuberculousEA,
  title={Tuberculous effusion: ADA activity correlates with CD4+ cell numbers in the fluid and the pleura.},
  author={Mina Gaga and George Papamichalis and Petros Bakakos and Panagiota I Latsi and Irini Samara and Nickolaos G. Koulouris and N Alchanatis and Dora Orphanidou},
  journal={Respiration; international review of thoracic diseases},
  year={2005},
  volume={72 2},
  pages={160-5}
}
BACKGROUND Adenosine deaminase (ADA) is a commonly used marker in the diagnosis of tuberculous effusion and there is evidence that its production is linked to T cells and monocytes. Data on the correlation between ADA and T cells or macrophages in tuberculous effusions are conflicting. Furthermore, no studies have examined a possible correlation between pleural tissue infiltration and ADA. OBJECTIVES We undertook this study to examine cell subsets in the fluid and the pleura in tuberculous… CONTINUE READING